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Local Delivery of the K(Ca)3.1 Blocker, TRAM-34, Prevents Acute Angioplasty-Induced Coronary Smooth Muscle Phenotypic Modulation and Limits Stenosis

OBJECTIVE: We previously demonstrated that upregulation of intermediate-conductance Ca(2+)-activated K(+) channels (K(Ca)3.1) is necessary for mitogen-induced phenotypic modulation in isolated porcine coronary smooth muscle cells (SMCs). The objective of the present study was to determine the role o...

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Detalhes bibliográficos
Main Authors: Tharp, D.L., Wamhoff, B.R., Wulff, H., Raman, G., Cheong, A., Bowles, D.K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652246/
https://ncbi.nlm.nih.gov/pubmed/18309114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.155796
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