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Chromatin modifications as therapeutic targets in MLL-rearranged Leukemia

MLL-rearranged leukemias exemplify malignancies with perturbations of the epigenetic landscape. Specific chromatin modifications that aid in the perpetuation of MLL-fusion gene driven oncogenic programs are being defined, presenting novel avenues for therapeutic intervention. Proof-of-concept studie...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Deshpande, Aniruddha J., Bradner, James, Armstrong, Scott A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034385/
https://ncbi.nlm.nih.gov/pubmed/22867873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.06.002
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