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Chromatin modifications as therapeutic targets in MLL-rearranged Leukemia
MLL-rearranged leukemias exemplify malignancies with perturbations of the epigenetic landscape. Specific chromatin modifications that aid in the perpetuation of MLL-fusion gene driven oncogenic programs are being defined, presenting novel avenues for therapeutic intervention. Proof-of-concept studie...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034385/ https://ncbi.nlm.nih.gov/pubmed/22867873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.06.002 |
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