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An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma

While advanced surgical techniques, radiation therapy and chemotherapeutic regimens provide a tangible benefit for patients with glioblastoma (GBM), the average survival from the time of diagnosis remains less than 15 months. Current therapy for GBM is limited by the nonspecific nature of treatment,...

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Main Authors: Gedeon, Patrick C, Choi, Bryan D, Hodges, Tiffany R, Mitchell, Duane A, Bigner, Darell D, Sampson, John H
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034273/
https://ncbi.nlm.nih.gov/pubmed/23927666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17512433.2013.811806
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