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Tumor-specific Immunotherapy Targeting the EGFRvIII Mutation in Patients with Malignant Glioma

Conventional therapies for malignant gliomas (MGs) fail to target tumor cells exclusively, such that their efficacy is ultimately limited by non-specific toxicity. Immunologic targeting of tumor-specific gene mutations, however, may allow more precise eradication of neoplastic cells. The epidermal g...

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Detalhes bibliográficos
Main Authors: Sampson, John H., Archer, Gary E., Mitchell, Duane A., Heimberger, Amy B., Bigner, Darell D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633865/
https://ncbi.nlm.nih.gov/pubmed/18539480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2008.04.001
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