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Tumor-specific Immunotherapy Targeting the EGFRvIII Mutation in Patients with Malignant Glioma

Conventional therapies for malignant gliomas (MGs) fail to target tumor cells exclusively, such that their efficacy is ultimately limited by non-specific toxicity. Immunologic targeting of tumor-specific gene mutations, however, may allow more precise eradication of neoplastic cells. The epidermal g...

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Autors principals: Sampson, John H., Archer, Gary E., Mitchell, Duane A., Heimberger, Amy B., Bigner, Darell D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633865/
https://ncbi.nlm.nih.gov/pubmed/18539480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2008.04.001
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