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Tumor-specific Immunotherapy Targeting the EGFRvIII Mutation in Patients with Malignant Glioma

Conventional therapies for malignant gliomas (MGs) fail to target tumor cells exclusively, such that their efficacy is ultimately limited by non-specific toxicity. Immunologic targeting of tumor-specific gene mutations, however, may allow more precise eradication of neoplastic cells. The epidermal g...

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Autores principales: Sampson, John H., Archer, Gary E., Mitchell, Duane A., Heimberger, Amy B., Bigner, Darell D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633865/
https://ncbi.nlm.nih.gov/pubmed/18539480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2008.04.001
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