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O-Glycosylation regulates polarized secretion by modulating Tango1 stability

Polarized secretion is crucial in many tissues. The conserved protein modification, O-glycosylation, plays a role in regulating secretion. However, the mechanisms by which this occurs are unknown. Here, we demonstrate that an O-glycosyltransferase functions as a novel regulator of secretion and secr...

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Detalhes bibliográficos
Principais autores: Zhang, Liping, Syed, Zulfeqhar Ali, van Dijk Härd, Iris, Lim, Jae-Min, Wells, Lance, Ten Hagen, Kelly G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034226/
https://ncbi.nlm.nih.gov/pubmed/24799692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322264111
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