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O-glycosylation modulates integrin and FGF signaling by influencing the secretion of basement membrane components

Extracellular microenvironments play crucial roles in modulating cell interactions during development. Here we discover that a conserved protein modification (O-glycosylation) influences extracellular matrix (ECM) composition during mammalian organogenesis, affecting integrin signaling and FGF-media...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tian, E, Hoffman, Matthew P., Ten Hagen, Kelly G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533247/
https://ncbi.nlm.nih.gov/pubmed/22643896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1874
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