Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation

The SARS-CoV-2 coronavirus responsible for the global pandemic contains a unique furin cleavage site in the spike protein (S) that increases viral infectivity and syncytia formation. Here, we show that O-glycosylation near the furin cleavage site is mediated by specific members of the GALNT enzyme f...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:bioRxiv
Päätekijät: Zhang, Liping, Mann, Matthew, Syed, Zulfeqhar, Reynolds, Hayley M., Tian, E, Samara, Nadine L., Zeldin, Darryl C., Tabak, Lawrence A., Ten Hagen, Kelly G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872346/
https://ncbi.nlm.nih.gov/pubmed/33564758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.05.429982
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia