Pharmacological or genetic orexin1 receptor inhibition attenuates MK-801 induced glutamate release in mouse cortex

The orexin/hypocretin neuropeptides are produced by a cluster of neurons within the lateral posterior hypothalamus and participate in neuronal regulation by activating their receptors (OX1 and OX2 receptors). The orexin system projects widely through the brain and functions as an interface between m...

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Main Authors: Aluisio, Leah, Fraser, Ian, Berdyyeva, Tamara, Tryputsen, Volha, Shireman, Brock T., Shoblock, James, Lovenberg, Timothy, Dugovic, Christine, Bonaventure, Pascal
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033200/
https://ncbi.nlm.nih.gov/pubmed/24904253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00107
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