Pharmacological or genetic orexin1 receptor inhibition attenuates MK-801 induced glutamate release in mouse cortex

The orexin/hypocretin neuropeptides are produced by a cluster of neurons within the lateral posterior hypothalamus and participate in neuronal regulation by activating their receptors (OX1 and OX2 receptors). The orexin system projects widely through the brain and functions as an interface between m...

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Detalhes bibliográficos
Main Authors: Aluisio, Leah, Fraser, Ian, Berdyyeva, Tamara, Tryputsen, Volha, Shireman, Brock T., Shoblock, James, Lovenberg, Timothy, Dugovic, Christine, Bonaventure, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033200/
https://ncbi.nlm.nih.gov/pubmed/24904253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00107
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