Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors

[Image: see text] Members of the bromodomain and extra terminal (BET) family of proteins are essential for the recognition of acetylated lysine (KAc) residues in histones and have emerged as promising drug targets in cancer, inflammation, and contraception research. In co-crystallization screening c...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ember, Stuart W. J., Zhu, Jin-Yi, Olesen, Sanne H., Martin, Mathew P., Becker, Andreas, Berndt, Norbert, Georg, Gunda I., Schönbrunn, Ernst
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2014
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032195/
https://ncbi.nlm.nih.gov/pubmed/24568369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500072z
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