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CD103−CD11b+ dendritic cells regulate the sensitivity of CD4 T cell responses to bacterial flagellin

Toll-like receptor 5 (TLR5) has been widely studied in an inflammatory context, but the effect of TLR5 on the adaptive response to bacterial flagellin has received considerably less attention. Here, we demonstrate that TLR5 expression by DCs allows a 1000-fold enhancement of T cell sensitivity to fl...

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Autors principals: Atif, Shaikh M., Uematsu, Satoshi, Akira, Shizuo, McSorley, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032068/
https://ncbi.nlm.nih.gov/pubmed/23632327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.25
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