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Direct Stimulation of tlr5(+/+) CD11c(+) Cells Is Necessary for the Adjuvant Activity of Flagellin
Flagellin is a highly effective adjuvant, but the cellular mechanism underlying this activity remains uncertain. More specifically, no consensus exists as to whether flagellin activates dendritic cells (DC) directly or indirectly. Intramuscular immunization with flagellin-OVA fusion protein resulted...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770462/ https://ncbi.nlm.nih.gov/pubmed/19494277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804225 |
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