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Enhanced Antigen Processing of Flagellin Fusion Proteins Promotes the Antigen-Specific CD8(+) T Cell Response Independently of TLR5 and MyD88
Flagellin is a highly effective adjuvant for CD4(+) T cell and humoral immune responses. However, there is conflicting data in the literature regarding the ability of flagellin to promote a CD8(+) T cell response. In this article, we report that immunization of wild-type, TLR5(−/−), and MyD88(−/−) a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743533/ https://ncbi.nlm.nih.gov/pubmed/21515787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001855 |
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