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Schistosoma mansoni Egg Antigen-Mediated Modulation of Toll-Like Receptor (TLR)-Induced Activation Occurs Independently of TLR2, TLR4, and MyD88

Unlike most pathogens, helminth parasites and their products induce strong Th2 responses, and dendritic cells (DCs) and macrophages exposed to helminth antigens generally fail to produce interleukin-12. Rather, it has been shown that helminth products such as soluble egg antigens (SEA; a soluble ext...

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Bibliographic Details
Main Authors: Kane, Colleen M., Jung, Euihye, Pearce, Edward J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583582/
https://ncbi.nlm.nih.gov/pubmed/18824534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00497-08
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