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Direct Stimulation of tlr5(+/+) CD11c(+) Cells Is Necessary for the Adjuvant Activity of Flagellin
Flagellin is a highly effective adjuvant, but the cellular mechanism underlying this activity remains uncertain. More specifically, no consensus exists as to whether flagellin activates dendritic cells (DC) directly or indirectly. Intramuscular immunization with flagellin-OVA fusion protein resulted...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770462/ https://ncbi.nlm.nih.gov/pubmed/19494277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804225 |
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