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TLR5 functions as an endocytic receptor to enhance flagellin-specific adaptive immunity

Innate immune activation via Toll-like Receptors (TLRs) induces dendritic cell maturation and secretion of inflammatory mediators, generating favorable conditions for naïve T cell activation. Here, we demonstrate a previously unknown function for TLR5, namely that it enhances MHC class-II presentati...

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Detalhes bibliográficos
Main Authors: Letran, Shirdi E., Lee, Seung-Joo, Shaikh, Atif, Uematsu, Satoshi, Akira, Shizuo, McSorley, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652676/
https://ncbi.nlm.nih.gov/pubmed/21182074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040717
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