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Induction of adaptive immunity by flagellin does not require robust activation of innate immunity

The ability of Toll-like Receptor (TLR) agonists to promote adaptive immune responses is attributed to their ability to robustly activate innate immunity. However, it has been observed that, for adjuvants in actual use in research and vaccination, TLR signaling is dispensable for generating humoral...

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Bibliografiske detaljer
Main Authors: Sanders, Catherine J., Franchi, Luigi, Yarovinsky, Felix, Uematsu, Satoshi, Akira, Shizuo, Núñez, Gabriel, Gewirtz, Andrew T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734905/
https://ncbi.nlm.nih.gov/pubmed/19152336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838804
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