Rapid CD4(+) T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9

Toll-like receptors (TLRs) can recognize microbial patterns and utilize adaptor molecules, such as-MyD88 or (TRIF TIR-domain-containing adapter-inducing interferon-β), to initiate downstream signaling that ultimately affects the initiation of adaptive immunity. In addition to this inflammatory role,...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Atif, Shaikh M, Lee, Seung-Joo, Li, Lin-Xi, Uematsu, Satoshi, Akira, Shizuo, Gorjestani, Sara, Lin, Xin, Schweighoffer, Edina, Tybulewicz, Victor L J, McSorley, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Innate Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324162/
https://ncbi.nlm.nih.gov/pubmed/25430631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444744
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