Intestinal CD103(+)CD11b(+) cDC2 Conventional Dendritic Cells Are Required for Primary CD4(+) T and B Cell Responses to Soluble Flagellin

Systemic immunization with soluble flagellin (sFliC) from Salmonella Typhimurium induces mucosal responses, offering potential as an adjuvant platform for vaccines. Moreover, this engagement of mucosal immunity is necessary for optimal systemic immunity, demonstrating an interaction between these tw...

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Udgivet i:Front Immunol
Main Authors: Flores-Langarica, Adriana, Cook, Charlotte, Müller Luda, Katarzyna, Persson, Emma K., Marshall, Jennifer L., Beristain-Covarrubias, Nonantzin, Yam-Puc, Juan Carlos, Dahlgren, Madelene, Persson, Jenny J., Uematsu, Satoshi, Akira, Shizuo, Henderson, Ian R., Lindbom, Bengt Johansson, Agace, William, Cunningham, Adam F.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199373/
https://ncbi.nlm.nih.gov/pubmed/30386346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02409
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