Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the Death Receptor pathway

The tumor necrosis factor related apoptosis-inducing ligand (TRAIL) causes cancer cell death, but many cancers, including pancreatic cancer, are resistant to TRAIL therapy. A combination of TRAIL and the diterpene triepoxide, triptolide, is effective in inducing pancreatic cancer cell death. Triptol...

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Hlavní autoři: Chen, Zhiyu, Sangwan, Veena, Banerjee, Sulagna, Chugh, Rohit, Dudeja, Vikas, Vickers, Selwyn M., Saluja, Ashok K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028717/
https://ncbi.nlm.nih.gov/pubmed/24662747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.03.016
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