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Molecular dissection of the domain architecture and catalytic activities of human PrimPol
PrimPol is a primase–polymerase involved in nuclear and mitochondrial DNA replication in eukaryotic cells. Although PrimPol is predicted to possess an archaeo-eukaryotic primase and a UL52-like zinc finger domain, the role of these domains has not been established. Here, we report that the proposed...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027207/ https://ncbi.nlm.nih.gov/pubmed/24682820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku214 |
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