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Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity
Synthetic short interfering RNA (siRNA) oligonucleotides can trigger the RNA interference pathway and lead to selective gene silencing. Despite considerable enthusiasm and investment, formidable challenges remain that may deter translating this breakthrough discovery into clinical applications. In p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026564/ https://ncbi.nlm.nih.gov/pubmed/24872690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S57449 |
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