Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity

Synthetic short interfering RNA (siRNA) oligonucleotides can trigger the RNA interference pathway and lead to selective gene silencing. Despite considerable enthusiasm and investment, formidable challenges remain that may deter translating this breakthrough discovery into clinical applications. In p...

Full description

Saved in:
Bibliographic Details
Main Authors: Konca, Yeliz Utku, Kirshenbaum, Kent, Zuckermann, Ronald N
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026564/
https://ncbi.nlm.nih.gov/pubmed/24872690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S57449
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items