Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity

Synthetic short interfering RNA (siRNA) oligonucleotides can trigger the RNA interference pathway and lead to selective gene silencing. Despite considerable enthusiasm and investment, formidable challenges remain that may deter translating this breakthrough discovery into clinical applications. In p...

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Bibliografske podrobnosti
Main Authors: Konca, Yeliz Utku, Kirshenbaum, Kent, Zuckermann, Ronald N
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026564/
https://ncbi.nlm.nih.gov/pubmed/24872690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S57449
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