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Molecular and Functional Consequences of Mutations in the Central Helix of Cardiac Troponin C

The objective of this work was to investigate the role of acidic residues within the exposed middle segment of the central helix of cTnC in (1) cTnC-cTnI interactions, (2) Ca(2+) binding and exchange with the regulatory N-domain of cTnC in increasingly complex biochemical systems, and (3) ability of...

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Hlavní autoři: Swindle, Nicholas, Albury, Acchia N. J., Baroud, Belal, Burney, Maryam, Tikunova, Svetlana B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026335/
https://ncbi.nlm.nih.gov/pubmed/24650606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.03.004
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