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Molecular and Functional Consequences of Mutations in the Central Helix of Cardiac Troponin C
The objective of this work was to investigate the role of acidic residues within the exposed middle segment of the central helix of cTnC in (1) cTnC-cTnI interactions, (2) Ca(2+) binding and exchange with the regulatory N-domain of cTnC in increasingly complex biochemical systems, and (3) ability of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026335/ https://ncbi.nlm.nih.gov/pubmed/24650606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.03.004 |
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