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Effect of Hypertrophic Cardiomyopathy-Linked Troponin C Mutations on the Response of Reconstituted Thin Filaments to Calcium upon Troponin I Phosphorylation()

The objective of this work was to investigate the effect of hypertrophic cardiomyopathy-linked A8V and E134D mutations in cardiac troponin C (cTnC) on the response of reconstituted thin filaments to calcium upon phosphorylation of cardiac troponin I (cTnI) by protein kinase A. The phosphorylation of...

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Detalhes bibliográficos
Main Authors: Albury, Acchia N. J., Swindle, Nicholas, Swartz, Darl R., Tikunova, Svetlana B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341542/
https://ncbi.nlm.nih.gov/pubmed/22489623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300187k
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