Loading...

Macrocyclic Peptoid–Peptide Hybrids as Inhibitors of Class I Histone Deacetylases

[Image: see text] We report the design, synthesis, and biological evaluation of the first macrocyclic peptoid-containing histone deacetylase (HDAC) inhibitors. The compounds selectively inhibit human class I HDAC isoforms in vitro, with no inhibition of the tubulin deacetylase activity associated wi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Olsen, Christian A., Montero, Ana, Leman, Luke J., Ghadiri, M. Reza
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2012
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025818/
https://ncbi.nlm.nih.gov/pubmed/24900543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300162r
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!