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Nonpeptide Macrocyclic Histone Deacetylase Inhibitors

Inhibition of Histone Deacetylases inhibitors (HDACi) hold great promise in cancer therapy due to their demonstrated ability to arrest proliferation of nearly all transformed cell types. Of the several structurally distinct small molecules HDACi reported, macrocyclic depsipeptides have the most comp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Oyelere, Adegboyega K., Chen, Po C., Guerrant, William, Mwakwari, Sandra C., Hood, Rebecca, Zhang, Yunzhe, Fan, Yuhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636857/
https://ncbi.nlm.nih.gov/pubmed/19093884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801128g
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