Nonpeptide Macrocyclic Histone Deacetylase Inhibitors

Inhibition of Histone Deacetylases inhibitors (HDACi) hold great promise in cancer therapy due to their demonstrated ability to arrest proliferation of nearly all transformed cell types. Of the several structurally distinct small molecules HDACi reported, macrocyclic depsipeptides have the most comp...

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Bibliografiske detaljer
Main Authors: Oyelere, Adegboyega K., Chen, Po C., Guerrant, William, Mwakwari, Sandra C., Hood, Rebecca, Zhang, Yunzhe, Fan, Yuhong
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636857/
https://ncbi.nlm.nih.gov/pubmed/19093884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801128g
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