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Nonpeptide Macrocyclic Histone Deacetylase Inhibitors

Inhibition of Histone Deacetylases inhibitors (HDACi) hold great promise in cancer therapy due to their demonstrated ability to arrest proliferation of nearly all transformed cell types. Of the several structurally distinct small molecules HDACi reported, macrocyclic depsipeptides have the most comp...

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Autori principali: Oyelere, Adegboyega K., Chen, Po C., Guerrant, William, Mwakwari, Sandra C., Hood, Rebecca, Zhang, Yunzhe, Fan, Yuhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636857/
https://ncbi.nlm.nih.gov/pubmed/19093884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801128g
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