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Dual Targeting of Histone Deacetylase and Topoisomerase II with Novel Bifunctional Inhibitors

Strategies to ameliorate the flaws of current chemotherapeutic agents, while maintaining potent anticancer activity, are of particular interest. Agents which can modulate multiple targets may have superior utility and fewer side effects than current single-target drugs. To explore the prospect in ca...

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Detalhes bibliográficos
Main Authors: Guerrant, William, Patil, Vishal, Canzoneri, Joshua C., Oyelere, Adegboyega K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306125/
https://ncbi.nlm.nih.gov/pubmed/22260166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200799p
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