Dual-Acting Histone Deacetylase-Topoisomerase I Inhibitors

Current chemotherapy regimens are comprised mostly of single-target drugs which are often plagued by toxic side effects and resistance development. A pharmacological strategy for circumventing these drawbacks could involve designing multivalent ligands that can modulate multiple targets while avoidi...

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Detaylı Bibliyografya
Asıl Yazarlar: Guerrant, William, Patil, Vishal, Canzoneri, Joshua C., Yao, Li-Pan, Hood, Rebecca, Oyelere, Adegboyega K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657756/
https://ncbi.nlm.nih.gov/pubmed/23622981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.03.108
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