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Synthesis and Functionalization of Cyclic Sulfonimidamides: A Novel Chiral Heterocyclic Carboxylic Acid Bioisostere
[Image: see text] An efficient synthesis of aryl substituted cyclic sulfonimidamides designed as chiral nonplanar heterocyclic carboxylic acid bioisosteres is described. The cyclic sulfonimidamide ring system could be prepared in two steps from a trifluoroacetyl protected sulfinamide and methyl este...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American
Chemical Society
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025735/ https://ncbi.nlm.nih.gov/pubmed/24900513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml3000935 |
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