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S-Methylidene Agents: Preparation of Chiral Non-Racemic Heterocycles

Reaction of sulfur ylide with aldehyde, imine, and ketone functionality affords the desired three-membered heterocycle in excellent yield. The sulfur ylide is generated in situ upon decarboxylation of carboxymethylsulfonium betaine functionality. Of the seven carboxymethylsulfonium betaine derivativ...

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Detalhes bibliográficos
Main Authors: Forbes, David C., Bettigeri, Sampada V., Patrawala, Samit A., Pischek, Susanna C., Standen, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657720/
https://ncbi.nlm.nih.gov/pubmed/20049065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.10.019
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