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Highly Stereoselective Methylene Transfers onto Butanediacetal-Protected Chiral Non-Racemic Sulfinyl Imines Using S-Ylide Technology

Reaction of sulfur ylide with chiral non-racemic imine afforded the desired aziridine in excellent yield. Diastereomeric ratios of >95:5 were obtained. Both enantiomeric lines of the butanediacetal-protected chiral non-racemic sulfinyl imines were examined. The sulfur ylides were generated in sit...

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Detalhes bibliográficos
Main Authors: Forbes, David C., Bettigeri, Sampada V., Pischek, Susanna C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586643/
https://ncbi.nlm.nih.gov/pubmed/19319433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b822779a
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