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On the origin of the stereoselectivity in chiral amide-based ammonium ylide-mediated epoxidations

ABSTRACT: Detailed DFT studies provide an in-depth mechanistic understanding for the use of chiral amide-based ammonium ylides in epoxidation reactions. It is shown that the used chiral auxiliary efficiently shields one face of the ylide, which thus results in an extraordinarily high stereoselectivi...

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Detalhes bibliográficos
Publicado no:Monatsh Chem
Main Authors: Novacek, Johanna, Robiette, Raphaël, Waser, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225234/
https://ncbi.nlm.nih.gov/pubmed/28127093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1866-8
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