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On the origin of the stereoselectivity in chiral amide-based ammonium ylide-mediated epoxidations

ABSTRACT: Detailed DFT studies provide an in-depth mechanistic understanding for the use of chiral amide-based ammonium ylides in epoxidation reactions. It is shown that the used chiral auxiliary efficiently shields one face of the ylide, which thus results in an extraordinarily high stereoselectivi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Monatsh Chem
Prif Awduron: Novacek, Johanna, Robiette, Raphaël, Waser, Mario
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Vienna 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225234/
https://ncbi.nlm.nih.gov/pubmed/28127093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1866-8
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