טוען...
CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120(IIIB) binding to the cell surface
CCR5 and CXCR4, the respective cell surface coreceptors of R5 and X4 HIV-1 strains, both form heterodimers with CD4, the principal HIV-1 receptor. Using several resonance energy transfer techniques, we determined that CD4, CXCR4, and CCR5 formed heterotrimers, and that CCR5 coexpression altered the...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4024905/ https://ncbi.nlm.nih.gov/pubmed/24778234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322887111 |
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