HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation

HIV type 1 (HIV-1) uses the chemokine receptors CCR5 and CXCR4 as coreceptors for entry into target cells. Here we show that the HIV-1 envelope gp120 (Env) activates multiple ionic signaling responses in primary human macrophages, which are important targets for HIV-1 in vivo. Env from both CCR5-dep...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Liu, Qing-Hua, Williams, Darlisha A., McManus, Carrie, Baribaud, Frédéric, Doms, Robert W., Schols, Dominique, De Clercq, Erik, Kotlikoff, Michael I., Collman, Ronald G., Freedman, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18318/
https://ncbi.nlm.nih.gov/pubmed/10758170
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados