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Identification of gp120 Binding Sites on CXCR4 by Using CD4-Independent Human Immunodeficiency Virus Type 2 Env Proteins

Human immunodeficiency virus (HIV) and simian (SIV) immunodeficiency virus entry is mediated by binding of the viral envelope glycoprotein (Env) to CD4 and chemokine receptors, CCR5 and/or CXCR4. CD4 induces extensive conformational changes that expose and/or induce formation of a chemokine receptor...

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Detalhes bibliográficos
Main Authors: Lin, George, Baribaud, Frédéric, Romano, Josephine, Doms, Robert W., Hoxie, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140809/
https://ncbi.nlm.nih.gov/pubmed/12502809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.931-942.2003
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