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Chemokine Co-Receptor CCR5/CXCR4-Dependent Modulation of Kv2.1 Channel Confers Acute Neuroprotection to HIV-1 Glycoprotein gp120 Exposure

Infection with human immunodeficiency virus-1 (HIV-1) within the brain has long been known to be associated with neurodegeneration and neurocognitive disorder (referred as HAND), a condition characterized in its early stages by declining cognitive function and behavioral disturbances. Mechanisticall...

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Détails bibliographiques
Auteurs principaux: Shepherd, Andrew J., Loo, Lipin, Mohapatra, Durga P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782454/
https://ncbi.nlm.nih.gov/pubmed/24086760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076698
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