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Metabolism of Cyclopropavir and Ganciclovir in Human Cytomegalovirus-Infected Cells

Human cytomegalovirus (HCMV) is a widespread pathogen that can cause severe disease in immunologically immature and immunocompromised patients. The current standard of therapy for the treatment of HCMV infections is ganciclovir (GCV). However, high incidence rates of adverse effects are prevalent an...

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Détails bibliographiques
Auteurs principaux: Gentry, Brian G., Drach, John C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023802/
https://ncbi.nlm.nih.gov/pubmed/24514084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02311-13
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