Mutations in the Pseudomonas aeruginosa Needle Protein Gene pscF Confer Resistance to Phenoxyacetamide Inhibitors of the Type III Secretion System

The type III secretion system (T3SS) is a clinically important virulence mechanism in Pseudomonas aeruginosa that secretes and translocates effector toxins into host cells, impeding the host's rapid innate immune response to infection. Inhibitors of T3SS may be useful as prophylactic or adjunct...

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Detaylı Bibliyografya
Asıl Yazarlar: Bowlin, Nicholas O., Williams, John D., Knoten, Claire A., Torhan, Matthew C., Tashjian, Tommy F., Li, Bing, Aiello, Daniel, Mecsas, Joan, Hauser, Alan R., Peet, Norton P., Bowlin, Terry L., Moir, Donald T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2014
Konular:
Mechanisms of Action: Physiological Effects
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023729/
https://ncbi.nlm.nih.gov/pubmed/24468789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02795-13
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