Discovery and Characterization of Inhibitors of Pseudomonas aeruginosa Type III Secretion

The type III secretion system (T3SS) is a clinically important virulence mechanism in Pseudomonas aeruginosa that secretes and translocates up to four protein toxin effectors into human cells, facilitating the establishment and dissemination of infections. To discover inhibitors of this important vi...

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Detalhes bibliográficos
Main Authors: Aiello, Daniel, Williams, John D., Majgier-Baranowska, Helena, Patel, Ishan, Peet, Norton P., Huang, Jin, Lory, Stephen, Bowlin, Terry L., Moir, Donald T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863679/
https://ncbi.nlm.nih.gov/pubmed/20176902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01598-09
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