Synthesis and structure-activity relationships of novel phenoxyacetamide inhibitors of the Pseudomonas aeruginosa type III secretion system (T3SS)

The increasing prevalence of drug-resistant bacterial infections is driving the discovery and development not only of new antibiotics, but also of inhibitors of virulence factors that are crucial for in vivo pathogenicity. One such virulence factor is the type III secretion system (T3SS), which play...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioorg Med Chem
Prif Awduron: Williams, John D., Torhan, Matthew C., Neelagiri, Venu, Brown, Carson, Bowlin, Nicholas O., Di, Ming, McCarthy, Courtney T., Aiello, Daniel, Peet, Norton P., Bowlin, Terry L., Moir, Donald T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339527/
https://ncbi.nlm.nih.gov/pubmed/25638499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.01.011
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