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Mutations in the Pseudomonas aeruginosa Needle Protein Gene pscF Confer Resistance to Phenoxyacetamide Inhibitors of the Type III Secretion System

The type III secretion system (T3SS) is a clinically important virulence mechanism in Pseudomonas aeruginosa that secretes and translocates effector toxins into host cells, impeding the host's rapid innate immune response to infection. Inhibitors of T3SS may be useful as prophylactic or adjunct...

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書誌詳細
主要な著者: Bowlin, Nicholas O., Williams, John D., Knoten, Claire A., Torhan, Matthew C., Tashjian, Tommy F., Li, Bing, Aiello, Daniel, Mecsas, Joan, Hauser, Alan R., Peet, Norton P., Bowlin, Terry L., Moir, Donald T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023729/
https://ncbi.nlm.nih.gov/pubmed/24468789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02795-13
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