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The interplay of DNA methylation over time with Th2 pathway genetic variants on asthma risk and temporal asthma transition
BACKGROUND: Genetic effects on asthma of genes in the T-helper 2 (Th2) pathway may interact with epigenetic factors including DNA methylation. We hypothesized that interactions between genetic variants and methylation in genes in this pathway (IL4, IL4R, IL13, GATA3, and STAT6) influence asthma risk...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023182/ https://ncbi.nlm.nih.gov/pubmed/24735657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-6-8 |
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