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Role of the Cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) Domain in Trafficking and Stabilization of Kv11.1 Channels

The N-terminal cytoplasmic region of the Kv11.1a potassium channel contains a Per-Arnt-Sim (PAS) domain that is essential for the unique slow deactivation gating kinetics of the channel. The PAS domain has also been implicated in the assembly and stabilization of the assembled tetrameric channel, wi...

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Detalhes bibliográficos
Main Authors: Ke, Ying, Hunter, Mark J., Ng, Chai Ann, Perry, Matthew D., Vandenberg, Jamie I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022852/
https://ncbi.nlm.nih.gov/pubmed/24695734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531277
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